Epilepsy Research Projects - Epilepsy London

Our current epilepsy research projects involves the acquisition and collation of clinical data via MRI, EEG and TMS. For more information on our current projects, please click on the projects listed below.

EEG@Home Epilepsy Project KCL

EEG@HOME

EEG@HOME aims to develop a safety and easy procedure that will allow patient with epilepsy to collect physiological data independently and unsupervised at home for long period. Participant will be asked to use different wearable solutions at home to acquire non-invasive measures related with the occurrence of seizures.

Network patterns of the EEG microstructure

The microstructural EEG elements and their topographies relate with many neurophysiological functions of the brain and can reveal neurological abnormalities. To reveal dysfunctional network properties of the epilepsy EEG microstructure, we develop computational tools that make use of machine learning and graph theory techniques.

Remote of Disease and Relapse in Central Nervous System Disorders

RADAR-CNS is a major international research project, which aims to develop new ways of measuring major diseases including depressive disorder, epilepsy and multiple sclerosis using wearable devices and smartphone technology.

Subcutaneous EEG

In this study, we will use innovative minimally-invasive subcutaneous EEG, which is implanted in a very brief minimally-invasive local anaesthetic procedure, and is subsequently invisible to an observer.

Understanding care pathways and clinical outcomes in neurological disorders

This project aims to explore primary care: administrative and electronic health records to perform a detailed analysis of patient pathways and outcomes of patients with neurological disorders at King’s College Hospital.

Brain networks in epilepsy: Endophenotypes and Generative Models

Since there are growing evidences showing the role of the human brain networks in the initiation-and-termination of a seizure, the aim of this project is to investigate the dynamic changes of the brain networks in patients with epilepsy.

Investigation of brain networks in Absence Epilepsy and Juvenile Myoclonic Epilepsy

We are looking at brain networks involved in the clinical expression of absence epilepsy and in juvenile myoclonic epilepsy before and after treatment.

Quantifying brain network connections: a novel biomarker for idiopathic generalised epilepsies?

This project aims to measure the biophysical properties of white matter tracts that connect seizure-generating networks in idiopathic generalised epilepsies, using magnetic resonance imaging.

Cortical signatures of antiepileptic drugs: A pharmaco-TMS-EEG study

This project aims to identify cortical fingerprints of antiepileptic drugs activity in healthy individuals by means of TMS-EEG.

Brain Networks in Focal Epilepsy

This project aims to investigate brain network properties in temporal lobe epilepsy to identify network abnormalities related to epilepsy and potentially endophenotypical network properties present in relatives of patients with epilepsy.

Using MRI and EEG to investigate brain function in IGE

This research project aims to use magnetic resonance imaging (MRI) and electroencephalography (EEG) to investigate brain function in idiopathic generalised epilepsy (IGE).

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